منابع مشابه
Pharmacokinetic interactions between contraceptives and antiepileptic drugs
The occurrence of bi-directional drug interactions between antiepileptic drugs (AEDs) and combined oral contraceptives (OCs) pose potential risks of un-intended pregnancy and as well as seizure deterioration. It is well established that several of the older AEDs (carbamazepine, phenytoin and phenobarbital), are strong inducers of the hepatic cytochrome P450 (CYP) 3A4 enzyme system, and are asso...
متن کاملAntiepileptic Drugs Combination Therapy And Interactions
antiepileptic drugs combination therapy and interactions antiepileptic drugs combination therapy and interactions this page intentionally left blank chuyên khoa than antiepileptic drugs combination therapy and interactions josé e. cavazos, md phd san antonio va epilepsy center of 40 combination therapy in epilepsy : what, when, how and the importance of drug interactions in epilepsy therapy dru...
متن کاملInteractions between antiepileptic drugs and hormones
Antiepileptic drugs (AEDs) are known to have endocrine side effects in both men and women. These can affect fertility, sexuality, thyroid function, and bone health, all functions of major importance for well-being and quality of life. The liver enzyme inducing antiepileptic drugs (EIAEDs), like phenobarbital, phenytoin, and carbamazepine, and also valproate (VPA), a non-EIAED, are most likely t...
متن کاملClinically relevant drug interactions with antiepileptic drugs.
Some patients with difficult-to-treat epilepsy benefit from combination therapy with two or more antiepileptic drugs (AEDs). Additionally, virtually all epilepsy patients will receive, at some time in their lives, other medications for the management of associated conditions. In these situations, clinically important drug interactions may occur. Carbamazepine, phenytoin, phenobarbital and primi...
متن کاملThird-generation antiepileptic drugs: mechanisms of action, pharmacokinetics and interactions.
This review briefly summarizes the information on the molecular mechanisms of action, pharmacokinetic profiles and drug interactions of novel (third-generation) antiepileptic drugs, including brivaracetam, carabersat, carisbamate, DP-valproic acid, eslicarbazepine, fluorofelbamate, fosphenytoin, ganaxolone, lacosamide, losigamone, pregabalin, remacemide, retigabine, rufinamide, safinamide, sele...
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ژورنال
عنوان ژورنال: Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
سال: 1984
ISSN: 0317-1671,2057-0155
DOI: 10.1017/s0317167100046151